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. 2015 Mar 24;10(3):e0121062. doi: 10.1371/journal.pone.0121062

Table 1. Rodent study: Specifications of the animals and their diets.

Energy content of the diet (% total kJ)
Study Species Strain Gender Age at sacrifice Intervention period Macro-nutrients CON HF/CAF
Rat studies
HF 45% Rats Wistar M 18 weeks 14 weeks Total CHO 70 36
Total fat 10 45 (mainly lard)
Total protein 20 19
HF 60% Rats Sprague-Dawley M 12 weeks 8 weeks Total CHO 70 20
Total fat 10 60 (mainly lard)
Total protein 20 20
CAF Rats Wistar M 18 weeks 12 weeks Total CHO 63 69 (mainly sugar)
Total fat 12 16
Total protein 25 15
Mouse study
HF 70% Mice C57BL/6J F 15 weeks 6 weeks Total CHO Standard chow <1
Total fat 72 (lard + corn oil)
Total protein 28

Abbreviations: M: male, F: female, CHO: carbohydrates, CON: control group, HF: high-fat group, CAF: cafeteria group.