Table 1. Rodent study: Specifications of the animals and their diets.
Energy content of the diet (% total kJ) | ||||||||
---|---|---|---|---|---|---|---|---|
Study | Species | Strain | Gender | Age at sacrifice | Intervention period | Macro-nutrients | CON | HF/CAF |
Rat studies | ||||||||
HF 45% | Rats | Wistar | M | 18 weeks | 14 weeks | Total CHO | 70 | 36 |
Total fat | 10 | 45 (mainly lard) | ||||||
Total protein | 20 | 19 | ||||||
HF 60% | Rats | Sprague-Dawley | M | 12 weeks | 8 weeks | Total CHO | 70 | 20 |
Total fat | 10 | 60 (mainly lard) | ||||||
Total protein | 20 | 20 | ||||||
CAF | Rats | Wistar | M | 18 weeks | 12 weeks | Total CHO | 63 | 69 (mainly sugar) |
Total fat | 12 | 16 | ||||||
Total protein | 25 | 15 | ||||||
Mouse study | ||||||||
HF 70% | Mice | C57BL/6J | F | 15 weeks | 6 weeks | Total CHO | Standard chow | <1 |
Total fat | 72 (lard + corn oil) | |||||||
Total protein | 28 |
Abbreviations: M: male, F: female, CHO: carbohydrates, CON: control group, HF: high-fat group, CAF: cafeteria group.