Table 2. Rodent study: Degree of obesity and glucose tolerance for the 4 diet-interventions.
| Study | Obesity | Glucose tolerance test | |||||
|---|---|---|---|---|---|---|---|
| Delta body weight (g) | End body weight (g) | Total AUC for glucose | Total AUC for insulin | ||||
| mmol.l-1.min | % increase | ng.ml-1.min | % increase | ||||
| Rat studies | |||||||
| HF 45% | CON (n = 8) | 323 ± 32 | 430 ± 34 | 999 ± 138 | 463 ± 134 | ||
| HF (n = 7) | 377 ± 61 * | 480 ± 69 $ | 1038 ± 127 | 4 | 533 ± 246 | 15 | |
| HF 60% | CON (n = 9) | 334 ± 48 | 486 ± 57 | 1144 ± 186 | 171 ± 74 | ||
| HF (n = 9) | 390 ± 44 * | 545 ± 47 * | 1397 ± 305 $ | 22 | 293 ± 139 * | 71 | |
| CAF a | CON (n = 11) | 255 ± 14 | 490 ± 47 | 579 ± 29 | 185 ± 28 | ||
| CAF (n = 11) | 305 ± 10* | 548 ± 55 * | 721 ± 44 * | 25 | 443 ± 39 * | 139 | |
| Mouse study | |||||||
| HF 70%a | CON (n = 8) | 3.9 ± 1.0 | 21.6 ± 1.9 | 168 ± 68 | |||
| HF (n = 8) | 6.1 ± 1.1 * | 23.1 ± 1.5 | 304 ± 127 * | 81 | not available | ||
| HF + ex (n = 6) | 4.7 ± 1.3 ** | 20.7 ± 1.4** | 280 ± 71 * | 67 | |||
Values are expressed as mean ± SD.
* p<0.05 versus CON,
** p<0.05 HF+ex versus HF and
$ p<0.1 versus CON.
Underlined % increase (compared to CON) are significant with p<0.05.
aData from the CAF and HF 70% study are obtained from respectively Vaisy et al. (27) and Deldicque et al.(28).
Abbreviations: CON: control group, HF: high-fat group, CAF: cafeteria group, HF+ex: high-fat+exercise group.