Table 2. The position in the genome, significance value, genes in the respective regions and the differences in the amino acid sequence for each gene in WE strain versus WA are described.
| Chromosome | QTL's | Position (cM) | LOD | Gene / Position | Position of amino acid change WA allele→WE allele |
|---|---|---|---|---|---|
| VI | Y034w | 65 | 3.85 | RIM15 /69.11 | 161 E → K; 240 S→G; 249 E→D; 251 T→S; 366 T→S; 399 V→A; 771 R→P; 1020 T→I; 1022 C→Y |
| BST1 | 84 | 5.11 | BST1 /84.14 | 202 A→T; 221 N→D; 253 A→P; 432 N→D; 438 K→M; 506 Q→L; 610K→R; 636S→W; 849 D→V | |
| BUD27 /90.9 | 32 Δ→E; 33D→Y; 75 S→F; 177 E→G; 182 D→E | ||||
| HTX10 | 111 | 4.95 | BLM10 /123.47 | 99 Q→R; 220 T→A; 258 G→A; 729 S→N; 759 I→V; 791 N→D; 902 C→Y; 1102 R→K; 1315 G→S; 1444 D→N; 1586 P→A; 1592 R→C; 1698 T→A; 1782 G→D; 1861 D→Y; 1900 I→V; 1971 M→I | |
| ARS605 | 136 | 4.93 | - | ||
| RPN11 | 153 | 4.50 | YFH7 /159.29 | 109 V→I; 138 A→T; 149 V→A | |
| YFR016c | 180 | 3.32 | FAB1 /184.50 | 120 S→N; 126 N→S; 333 A→S; 583 Δ→N; 1273 N→D; 1300 Y→H; 1524 G→E; 1604 R→M; 1780 P→S; 1878 I→M; 1882 S→A; 1884 Q→Δ | |
| ATG18 /194.81 | 195 N→S | ||||
| ROG3 | 196 | 2.40 | - | ||
| XI | TRP3 | 37 | 2.72 | CBT1 /47.15 | 29 S→G; 109 T→A |
| ARS1103 | 58 | 3.03 | - | ||
| YKT6 | 75 | 2.46 | - | ||
| FAS1 | 103 | 2.58 | - | ||
| TP05 | 121 | 3.10 | MRP49 /133.72 | 131 G→R | |
| PIR1 | 142 | 2.34 | RSM22 /159.45 | 228 E→K; 474 D→S; 619 S→N | |
| DBR1 /167.61 | 223 Q→R; 286 K→E; 325 N→D | ||||
| AVT3 | 173 | 1.16 | - |
Allele without mismatch (-).