Table 2. Drug-loaded amount, and experimental and simulate basal spacing of Na-MMT/amine-containing drugs complexes.
| System | Drug-loaded amount/ MMT (mg/g) | Experimental basal spacing (Å) | Simulate basal spacing (Å)** |
|---|---|---|---|
| Na-MMT/RVT | 114.0 | 17.9 | 17.62 |
| Na-MMT/DXZ | 247.2 | 24.2 | 23.98 |
| Na-MMT/5FU | 89.2 | 15.8 | 15.79 |
| Na-MMT/CLX | 175.5 | 17.5 | 18.07 |
| Na-MMT/ODP | 257.5 | 15.2 | - |
| Na-MMT/ACV | - | 12.9* | - |
| Na-MMT/DPS | 110.7 | 15.7 | 15.55 |
| Na-MMT/NTT | 230.7 | 16.9 | 16.51 |
| Na-MMT/PSA | - | 14.7* | - |
*No intercalation evident.
**Basal spacing results of the models closer to experimental results. Average basal spacing in 1 ns of molecular dynamics simulations.