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. 2015 Mar 24;10(3):e0120544. doi: 10.1371/journal.pone.0120544

Table 2. Microbiological data according to survival of critically ill cancer patients with pneumonia.

All Patients n = 325 (100%) Survivors n = 114 (35%) Nonsurvivors n = 211 (65%) P Value
Microbiological confirmation 169 (52%) 53 (47%) 116 (55%) 0.163
Adequate antibiotic therapy 1 136 (81%) 45 (85%) 91 (78%) 0.405
Positive blood culture 40 (24%) 15 (28%) 25 (22%) 0.338
Gram-negative bactéria 99 (59%) 36 (68%) 63 (54%) 0.130
Pseudomonas aeruginosa 41 (24%) 10 (19%) 31 (27%) 0.335
Klebsiella pneumoniae 15 (9%) 4 (8%) 11 (10%) 0.779
Gram-positive bactéria 69 (41%) 22 (42%) 47 (41%) 0.999
Staphylococcus aureus 42 (25%) 12 (23%) 30 (26%) 0.705
Streptococcus pneumoniae 21 (12%) 10 (19%) 11 (10%) 0.129
MR Pathogens 2 23 (14%) 6 (11%) 17 (15%) 0.636
MRSA 11 (7%) 3 (6%) 8 (7%) 0.999
ATS Guideline adherence 3 53 (16%) 25 (22%) 28 (13%) 0.058
Macrolide use 66 (20%) 30 (26%) 36 (17%) 0.060
Atypical pathogen coverage 116 (36%) 52 (46%) 64 (30%) 0.007
Only quinolone use 50 (15%) 22 (19%) 28 (13%) 0.197
Number of antimicrobial agentes
1 154 (47%) 45 (40%) 109 (52%) 0.037
2 126 (39%) 49 (43%) 77 (37%)
> 2 44 (14%) 17 (15%) 27 (13%)

1- Adequate empiric antibiotic treatment was based in the sensitivity test of the identified bacteria.

2- The MR pathogens were defined as non-susceptibility to at least one agent in three or more antimicrobial categories. [6,21]

3- ATS/IDSA guidelines adherence was based in definitions of empiric antimicrobial treatment for CAP and HCAP. [8,10], [10,17]