Expected value-of-information (in terms of potential infections averted) of knowing which nodes are initially infected, measured as the difference in expected number of infections under the best preventive strategy and the best reactive strategy. Shown for (A) Erdős-Rényi random networks with varying levels of connectivity: p = 0.8 (solid line), p = 0.4 (dashed line), p = 0.2 (dotted line); (B) the residential hotel network with varying levels of infectiousness: base (solid), high (dashed), and low (dotted); and (C) a network exhibiting community structure. Results are based on the average of 300 simulations with 10% of nodes initially infected.