Table 1. Influence of flavan-3-ols and proanthocyanidins from RA1 on the adhesion of P. gingivalis to KB cells in the coincubation adhesion assay.
Test compound | 1 | 3 | 4 | 5 | 6 | 7 | 8 | 12 | 14 | 15 |
---|---|---|---|---|---|---|---|---|---|---|
IC50 [μM] | >50 | >50 | >50 | >50 | 38.0 | >50 | 19.6 | 3.8 | 19.8 | >100 |
IC75[μM] | 30.0 |
Data represent IC50 resp. IC75 for compound 5. IC50: concentration of the test compound reducing the bacterial adhesion to 50%, related to the untreated control group; IC75: concentration of the test compound 5 reducing the bacterial adhesion to 75%, related to the untreated control group.