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. 2015 Mar 24;10(3):e0120321. doi: 10.1371/journal.pone.0120321

Fig 5. Expression of MMP-2 correlates negatively with miR-519d-3p in placental tissues.

Fig 5

(A) Quantitative real-time PCR analysis of MMP-2 mRNA expression in placentas from patients with PE (PE) and normal pregnancies (control). Relative expression of MMP-2 was normalized to β-actin. Data is mean ± SEM of three independent experiments; *, P < 0.05 vs. control, Student’s t-test. (B) The correlation between miR-519d-3p and MMP-2 expression in placentas from patients with PE was analyzed using the Pearson correlation and linear regression analysis. Relative expression of miR-519d and MMP-2 were normalized to U6 or β-actin, respectively.