FIG. 2.

Exaggerated expression of chemokines and cytokines after SEB exposure. Mice were exposed to either vehicle or SEB for 72 h and euthanized. The trachea was bound with a suture. Following the excision of the lung along with the trachea, 1 ml of ice-cold PBS was flushed through the trachea and collected as the broncheoalveolar lavage fluid (BALF). Cytokine and chemokine expression was analyzed using a Bioplex and the concentration quantified in pg/ml. Data are represented as mean ± SEM (n = 5) from 2 independent experiments. Statistical significance is indicated as follows ^*P < 0.05, ^**P < 0.01, ^***P < 0.001 (when compared with vehicle).