Table 2.
Metabolic characteristics of patients with urolithiasis and overweight or obesity (BMI Z-score ≥1) and with urolithiasis and a normal body weight (BMI Z-score <1)
| Demographic and metabolic characteristics | Urolithiasis group with BMI Z-score ≥1 (n = 97) | Urolithiasis group with BMI Z-score <1 (n = 381) | p |
|---|---|---|---|
| Age (years) | 14.27 (11.51–16.43) | 14.89 (11.14–16.85) | NS |
| Gender, n (female/male) | 53/44 | 221/160 | NSa |
| Urine volume (ml/kg/24 h) | 18.07 (12.50–23.15) | 22.58 (15.84–30.00) | <0.01 |
| Creatinine (mg/dL) | 0.60 (0.49–0.73) | 0.60 (0.48–0.73) | NS |
| Uric acid (mg/dL) | 4.98 (4.29–5.84) | 4.43 (3.82–5.21) | <0.01 |
| Cholesterol (mg/dL) | 171 (151–187) | 154.5 (135–185) | NS |
| Glucose (mg/dL) | 90 (85–93) | 88 (83–93) | NS |
| BRI (L−1) | 0.66 (0.14–3.01) | 1.13 (0.15–3.87) | NS |
| Urine pH | 6.40 (6.00–6.61) | 6.33 (6.05–6.60) | NS |
| GFR (ml/min/1.73 m2) | 126.46 (104.41–145.78) | 122.66 (100.64–143.67) | NS |
| Oxalate/cr. (mmol/g cr.) | 0.38 (0.24–0.65) | 0.47 (0.23–0.71) | NS |
| Citrate/cr. (mg/g cr.) | 461.86 (267.16–713.51) | 455.99 (278.10–697.4) | NS |
| Ca/cr. (mmol/g cr.) | 2.77 (1.84–5.48) | 3.63 (2.12–5.89) | NS |
| P/cr. (mmol/g cr.) | 19.63 (15.27–25.10) | 19.61 (15.54–26.02) | NS |
| Mg/cr. (mmol/g cr.) | 3.13 (2.43–4.04) | 3.39 (2.62–4.53) | NS |
| Uric acid/cr. | 0.44 (0.35–0.56) | 0.44 (0.36–0.57) | NS |
| Ca/citrate | 0.28 (0.15–0.56) | 0.32 (0.17–0.59) | NS |
Data are presented as the median with the IQR in parenthesis, unless otherwise indicated
aThe chi-square statistic was used