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. Author manuscript; available in PMC: 2015 Mar 25.
Published in final edited form as: FEMS Immunol Med Microbiol. 2009 Mar;55(2):271–279. doi: 10.1111/j.1574-695X.2008.00517.x

Fig. 3. Resolution of primary genital C. muridarum infection after rCPAF+CpG vaccination.

Fig. 3

Groups (5–6 mice/group) of C57BL/6 or μmT mice were vaccinated with three doses of rCPAF+CpG or mock-immunized with PBS. One month following final vaccination, mice were challenged i.vag. with 5 × 104 IFU of C. muridarum. At the indicated days following challenge, chlamydial shedding was measured and the numbers of chlamydial inclusion forming units (IFU) recovered from vaginal swabs are shown. Each symbol represents an individual animal. The number of animals in each group that had resolved the infection is indicated on the X-axis. * Significant differences between indicated groups (P < 0.05, Kruskall-Wallis test). Kaplan Meier survival analyses indicated significant differences between vaccinated and mock C57BL/6 animals (P = 0.0015), and differences between vaccinated and mock μmT animals (P = 0.0009). Results are representative of three independent experiments.