Table 3.
Bivariate demographic information by patients’ intake of PPI and H2RA, alone and in combination.
The patients in PPI+ H2RA treatment group have been excluded from PPI alone and H2RA alone groups. All statistical analyses were done in SAS version 9.2 (SAS Institute, Carey, NC). A two-tailed p≤0.05 was considered statistically significant.
| Characteristic | Overall N=596 |
PPI alone N=191 |
H2RA alone N=83 |
PPI and H2RA N=136 |
None N=186 |
|
|---|---|---|---|---|---|---|
| Age (years) | Mean (sd), Median, Range among users | 58.3 (11.3), 57, 21–92 | 59.2 (10.4), 58,33–86 | 57.2 (12.2), 55,21–86 | 56.3 (11.2), 55, 22–85 | 58.2 (11.4), 57, 27–92 |
| p value | 0.06 | 0.56 | 0.05 | 0.72 | ||
|
| ||||||
| Overall |
PPI alone N (% users) |
H2RA alone N (% users) |
PPI+H2RA N (% users) |
None N (% users) |
||
|
| ||||||
| Gender | Male | 448 | 152 (34%) | 60(13%) | 98(22%) | 138(31%) |
| Female | 148 | 39(26%) | 23(16%) | 38(26%) | 48(32%) | |
| p value | 0.09 | 0.51 | 0.34 | 0.71 | ||
| Primary Tumor Site | OC | 150 | 32(21%) | 43(29%) | 43(29%) | 32(21%) |
| OP | 251 | 67(27%) | 29(12%) | 60(24%) | 95(38%) | |
| HP, LAR | 135 | 65(48%) | 8(6%) | 23(17%) | 39(29%) | |
| NP, Other, Unknown | 58 | 27(47%) | 2(3%) | 10(17%) | 19(33%) | |
| p value | <0.0001 | <0.0001 | 0.08 | 0.01 | ||
| Stage | Early | 110 | 42(38%) | 16(15%) | 19(17%) | 33(30%) |
| Late | 482 | 148(31%) | 66(14%) | 117(24%) | 151(31%) | |
| Missing | 4 | |||||
| p value | 0.13 | 0.82 | 0.12 | 0.79 | ||
| Tstage | 0,1,2 | 244 | 78(32%) | 31(13%) | 51(21%) | 84(34%) |
| 3,4 | 305 | 96(31%) | 48(16%) | 78(26%) | 83(27%) | |
| X,x | 44 | 17(39%) | 3(7%) | 7(16%) | 17(39%) | |
| Missing | 3 | |||||
| p value | 0.63 | 0.22 | 0.22 | 0.10 | ||
| Smoking | Never | 145 | 39(27%) | 17(12%) | 45(31%) | 44(30%) |
| Former | 226 | 77(34%) | 33(15%) | 45(20%) | 71(31%) | |
| Current-quit within 1 month | 223 | 75(34%) | 32(14%) | 46(21%) | 70(31%) | |
| Missing | 2 | |||||
| p value | 0.30 | 0.70 | 0.03 | 0.97 | ||
| Race | White | 560 | 178(32%) | 79(14%) | 131(23%) | 172(31%) |
| Non-White | 34 | 13(38%) | 3(9%) | 5(15%) | 13(38%) | |
| Missing | 2 | |||||
| p value | 0.43 | 0.39 | 0.24 | 0.36 | ||
| Married Yes/No | Married | 369 | 138(37%) | 49(13%) | 81(22%) | 101(27%) |
| Not Married | 223 | 53(24%) | 33(15%) | 54(24%) | 83(37%) | |
| Missing | 4 | |||||
| p value | 0.0006 | 0.60 | 0.52 | 0.01 | ||
| Education Some College | HS or less | 236 | 74(31%) | 42(18%) | 50(21%) | 70(30%) |
| Some college or more | 305 | 102(33%) | 34(11%) | 74(24%) | 95(31%) | |
| Missing | 55 | |||||
| p value | 0.61 | 0.03 | 0.40 | 0.71 | ||
| County Median Income from Census | 30K or Below | 55 | 16(29%) | 8(15%) | 7(13%) | 24(44%) |
| Above 30K | 541 | 175(32%) | 75(14%) | 129(24%) | 162(30%) | |
| p value | 0.62 | 0.89 | 0.06 | 0.04 | ||
| Treatment | Surgery only | 68 | 25(37%) | 18(26%) | 9(13%) | 16(24%) |
| Radiation only | 31 | 15(48%) | 1(3%) | 3(10%) | 12(39%) | |
| Surgery + Radiation | 75 | 24(32%) | 13(17%) | 16(21%) | 22(29%) | |
| Radiation + Chemotherapy | 246 | 79(32%) | 20(8%) | 50(20%) | 97(39%) | |
| Radiation + Chemotherapy + Surgery | 176 | 48(27%) | 31(18%) | 58(33%) | 39(22%) | |
| p value | 0.18 | <0.0003 | 0.001 | 0.002 | ||