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. Author manuscript; available in PMC: 2015 Sep 24.
Published in final edited form as: Nat Commun. 2015 Mar 24;6:6448. doi: 10.1038/ncomms7448

Figure 4. M3-R agonists enhance odor-induced responses of OSNs.

Figure 4

(A) A single OSN was alternately stimulated by puffs of odorants+Ringer's solution (hollow rectangles in black), odorants+carbachol at 1 μM (filled rectangle in red) or 0.1 μM (filled rectangle in pink), or odorants+acetylcholine at 1 μM (filled rectangles in green) under voltage-clamp mode. All odorants were presented at a concentration of 100 μM. The two rows are sequential recordings from the same cell. (B) The peak current induced by odorants+agonist (averaged from all trials in each cell) is plotted against that induced by odorants+Ringer's solution. The identity line represents equal responses from the two stimuli. The holding potential was -65 mV for all neurons.