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. Author manuscript; available in PMC: 2015 Aug 1.
Published in final edited form as: Endocr Relat Cancer. 2015 Apr;22(2):239–248. doi: 10.1530/ERC-14-0539

Figure 3. ACWi rats exhibit reduced treatment related morbidity relative to ACI rats.

Figure 3

Female ACWi, ACI and COP rats were treated with E2 as described in Figure 1 and Materials and Methods. The impact of any treatment related morbidity other than mammary tumor burden on survival was evaluated as a function of duration of E2 treatment and the data were subjected to Kaplan-Meier analyses. Each plot illustrates the number of days separating initiation of E2 treatment and euthanasia due to undesired treatment related morbidity.