Figure 3.

(a and b) Tumor composed of marked verrucous hyperplasia of squamous epithelium with reduplication, down growths, pushing borders, and mild nuclear atypia; the clinicopathological picture was suggestive of a verrucous carcinoma (hematoxylin and eosin (H and E), ×20). (c) Verrucous carcinoma showing mild focal immunopositivity for p16 (H and E, ×10). (d) Figure showing the polymerase chain reaction (PCR) amplification of the sample deoxyribonucleic acid (DNA) showing human papillomavirus (HPV) infection using consensus primer GP5+ and GP6+ showing lane 1-7 in the PCR ladder; Lane 3 - positive control (HeLa cells), lane 4 - tumor sample; and lane 6 - negative control