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. 2015 Mar 12;14:59. doi: 10.1186/s12943-015-0298-0

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© Liu et al.; licensee BioMed Central. 2015

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Altered KCNJ2/Kir2.1 expression in SCLC cells. qRT-PCR (A) and Western blot (B) analyses showed forced KCNJ2/Kir2.1 expression in H69 and H446 cells after transfection of pcDNA3.1-KCNJ2, and KCNJ2/Kir2.1 inhibition in H69AR and H446AR cells by shKCNJ2-1or shKCNJ2-2. The bars represent the means ± SD of three independent experiments. **, P < 0.01 compared withthe corresponding NC cells transfected with pcDNA3.1 empty vector or shNC.