Fig 4.

Liver mRNA expression of mitochondrial biogenesis genes assessed by quantitative real-time PCR in each experimental group. Each bar represents the mean ± S.E. values of 10 and 15 animals in SCD and HFD, respectively. In each sample, the gene expression was normalized to the expression of cyclophilin A and multiplied by 100. Tfam: mitochondrial transcription factor A; PPARδ: peroxisome proliferator-activated receptor γ; PGC-1α: peroxisome proliferator-activated receptor gamma coactivator-1α; PGC-1β: peroxisome proliferator-activated receptor gamma coactivator-1β; NRF-1: nuclear respiratory factor 1; PPIA: peptidylprolyl isomerase A (cyclophilin A); NS: not significant.