Table 1.
Effect of histamine on contractility parameters in isolated ring preparations of various rabbit veins
| Vein | n | pD2 | Emax | P (Emax) | |
|---|---|---|---|---|---|
| 1 | Inferior vena cava (abdominal part) | 10 | 6.11 ± 0.10 | 17.8 ± 1.1 | |
| 2 | Saphenous vein | 12 | 5.73 ± 0.04 | 16.2 ± 0.4 | >0.05 1 versus 2 |
| 3 | Axillary vein | 5 | 6.07 ± 0.12 | 14.7 ± 0.3 | >0.052 versus 3 |
| 4 | Femoral vein | 7 | 6.03 ± 0.08 | 10.7 ± 0.8 | <0.053 versus 4 |
| 5 | Common iliac vein | 5 | 6.29 ± 0.11 | 9.5 ± 0.6 | >0.054 versus 5 |
| 6 | Inferior vena cava (thoracic part) | 7 | 5.57 ± 0.06 | 1.5 ± 0.1 | <0.015 versus 6 |
| 7 | Right superior vena cava | 7 | 5.77 ± 0.16 | 0.6 ± 0.1 | <0.056 versus 7 |
| 8 | Subclavian vein | 5 | 5.10 ± 2.60 | 0.5 ± 0.7 | >0.057 versus 8 |
| 9 | External iliac vein | 9 | 5.74 ± 0.07 | 0.3 ± 0.01 | >0.058 versus 9 |
Data are mean values ± S.E.M.
Analysis of statistical significance was performed with variance analysis (ANOVA) with the Newman–Keuls post-hoc test.
n: number of experiments; pD2: negative base 10 logarithms of EC50 values; Emax: maximum effect (mN/mm2); P: statistical significance.