Table 2.
Clinical and biomedical variables in blood serum of the subjects with or without pathological periodontal pockets (PD ≥4 mm)
| With PD ≥4 mm | Without PD ≥4 mm | ||
|---|---|---|---|
| (n = 14) | (n = 61) | ||
| Variables | Number (%) | Number (%) | P-value 1 |
| Presence of dental calculus | |||
| Supragingival | 8 (57) | 22 (36) | 0.151 |
| Subgingival | 4 (29) | 10 (16) | 0.586 |
| VPI | |||
| 0-25% | 8(57) | 47 (77) | |
| > 25% | 6 (43) | 14 (23) | 0.132 |
| BOP | |||
| 0-25% | 5 (36) | 47 (77) | |
| > 25% | 9 (64) | 1 (23) | 0.002 |
| Mean (SD) | Mean (SD) | ||
| Adiponectin (μg/ml) | 13.5 (74.3) | 12.3 (802) | 0.641 |
| PAI-1 Tot (ng/ml) | 42.8 (19.2) | 944 (6635) | 0.642 |
| IL-1β (pg/ml) | 0.8 (0.8) | 1.1 (4.1) | 0.819 |
| IL-6 (pg/ml) | 37.5 (44.9) | 10.5 (11.3) | <0.001 |
| IL-8 (pg/ml) | 15.2 (7.7) | 33.9 (106.8) | 0.548 |
| Leptin (ng/ml) | 66.3 (54,1) | 41.2 (23.0) | 0.018 |
| TNF-α (pg/ml) | 6.9 (2.5) | 6.8 (3.1) | 0.848 |
| MCP-1 (pg/ml) | 256 (104) | 464 (352) | 0.049 |
| Total cholesterol (mmol/l) | 3.9 (0.7) | 4.0 (0.7) | 0.645 |
| LDL/HDL quotient | 2.1 (1.0) | 2.2 (0.7) | 0.404 |
| Hba1c (mmol/mol) | 4.5 (0.4) | 4.6 (0.4) | 0.182 |
| CRP (mg/l) | 2.6 (2.7) | 4.7 (4.1) | 0.071 |
| TSH (mlU/l) | 3.9 (3.0) | 2.5 (1.1) | 0.004 |
| Blood pressure (mmHg) | |||
| -Systolic | 119 (9) | 116 (9) | 0.294 |
| -Diastolic | 74 (5) | 67 (7) | 0.008 |
| Insulin resistance Bergman | |||
| -Si (×10−4/min/pM) | 1.9 (1.3) | 1.5 (1.4) | 0.313 |
| -Air (pM) | 1930 (1782) | 3107 (3692) | 0.254 |
1ONEWAY ANOVA as statistical method.