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. 2015 Mar 23;3:11. doi: 10.1186/s40168-015-0075-8

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© McMurtry et al.; licensee BioMed Central. 2015

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Principal coordinate analysis (PCoA) of NEC compared to controls. Unweighted UniFrac uses phylogenetic information to compare specimens that can be visualized with PCoA plots. The gray circles represent the control specimens (n = 74), blue circles represent mild NEC specimens (n = 8), red circles represent severe NEC specimens (n = 7), and green circles represent lethal NEC specimens (n = 6). ANOSIM was used to evaluate the UniFrac distances of all NEC vs controls. Although the P value is statistically significant (P = 0.001), the R value (0.2309) suggests that the communities are essentially not separable. PC, principal coordinate.