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Potential steps in the development of Randall’s Plaques as described in the text. RUNX2, runt-related transcription factor 2; cbf-a1, core binding factor subunit alpha-1; MSX-2, Msh homebox 2; MGP, matrix gla protein; OPN, osteopontin; BMP, bone morphogenetic proteins; BSP, bone sialoprotein.
