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. Author manuscript; available in PMC: 2015 Mar 25.
Published in final edited form as: Curr Mol Imaging. 2014 Jul 1;3(2):88–105. doi: 10.2174/2211555203666141117233442

Figure 2.

Figure 2

Images of EGFR expression in three-dimensional cell constructs containing EGFR+ cells (MDA-MB-468) with and without antibody-conjugated nanospheres (a and c, respectively) and EGFR-cells (MDA-MB-435) with antibody-conjugated nanospheres (b). There was a significant increase in the photothermal signal from EGFR overexpressing cell constructs labeled with antibody conjugated nanospheres (d) compared to the two controls (EGFR+/Nanosphere-and EGFR-/Nanosphere+). N = 17 images for each group, (*, p < 0.0001). Pump power 8.5 kW/cm2. Reproduced with permission from (19). Copyright 2008, American Chemical Society.