Table 2. Women prescribed antibiotics versus never prescribed: time to cerebral palsy and/or epilepsy in childhood.

	Number mother-child pairs in analysis	Number (%) prescribed antibiotics		Number children with any cerebral palsy or epilepsy	Unadjusted hazard ratio (95% confidence interval)		Adjusted† hazard ratio (95% confidence interval)
All women	195,899	64,613	(33.0%)	1,170	1.20*	(1.06, 1.35)	1.04	(0.91, 1.19)
Women with a single respiratory tract infection‡	17,822	7,266	(40.8%)	83	0.99	(0.65, 1.51)	0.94	(0.62, 1.42)

*p<0.01

† Cox regression model adjusted for propensity score which included: hypertension, smoking/tobacco use, diabetes, age at delivery, year of delivery, Townsend quintile, treatment of chronic medical condition in pregnancy, alcohol problems, illicit drug use, obesity and potentially neurologically-damaging infection during pregnancy.

‡ Analysis cohort included women with a single respiratory tract infection who either received or did not receive a single antibiotic prescription within plus or minus three days of the recorded date of respiratory tract infection.