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. 2015 Mar 25;10(3):e0118833. doi: 10.1371/journal.pone.0118833

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© 2015 Majumdar et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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Fig 8 — Volume variation affects precision significantly at higher concentrations. Volume variability is simulated by assuming a normal distribution of well volumes with the standard deviation taken as a percentage of the mean well volume. Volumes of 865pl for 10,000 partitions were used in the simulation. Note that concentration at peak precision moves toward lower concentrations (increasing negative percentage) as volume variability increases.