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Typical Bell-shaped Dose-Response Curves for Effects of Xanthines on Open-Field Locomotor Activity in Mice (Daly, 1993). Caffeine (●), theophylline (□), 3,7-dimethyl-1-propargylxamhine (○). Activity measured for 60 min in a circular arena after intraperitoncal injection of xanthine to male NIH Swiss strain mice.
