Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Effects of Xanthines and the Adenosine Analog N6-R-phenylisopropyladenosine (R-PIA) on locomotor activity in mice (Daly, 1993). Open-field activity is for the second thirty minute period after intraperitoneal injections to Male ICR mice of xanthines alone or in combination with R-PIA (0.2 μmol/kg). Note the depressant effect of lowest dose of caffeine and stimulatory effect of R-PIA in combination with that dose of caffeine.
