Fig 3. TSA inhibits PDGF-induced RPE cell migration.

RPE cells treated with 0–0.7 μM TSA for 24 h were placed on the top of a fibronectin coated-Boyden chamber, with 10 ng/mL of PDGF and DMEM with 0.4% FBS added to the bottom chamber and incubated for 5 h. Four randomly chosen fields were counted per inserts, and the results presented are averages of the four fields from each insert from three independent experiments. TSA inhibits RPE cell migration at 0.5 and 0.7 μM. (*: t test p<0.05).