Fig 11. TSA reduces fluorescence leakage in laser-induced mouse CNV model.

After laser photocoagulation on day 0, C57Bl/6 mice received intra-peritoneal injections of either PBS or TSA (20 mg/kg) every 48 h for 7 or 14 days. (A, B) Angiogram pictures were taken on days 7 and 14, 3 min after a 0.1 mL of 2.5% fluorescein sodium injection. For both days 7 and 14, TSA-injected mice showed significantly less fluorescence leakage than PBS-treated mice. (*: t test p<0.05; n = 10 mice/group).