Fig 3. Specific IgG responses to Salmonella Typhimurium lipopolysaccharide and Bordetella pertussis toxin antigens in HEU and HUU children at different ages.

Levels of specific IgG titres were measured against STM LPS (3A) and PT (3B) in HEU and HUU at three time points, 6 months (during CTX prophylaxis), 12 months (At stopping CTX prophylaxis) and 18 months (6 months after CTX prophylaxis). X-axis represents age of children in months. Black horizontal bars represent medians. Black lines represent differences in the median titres between groups at each time point. Blue lines represent a significant increase in levels of IgG titres from baseline in each group. Significant differences are indicated in asterices: Fig. 3A # (p = 0.0013), ## (p = 0.0263), ### (p = 0.0038), Fig. 3B *(p = 0.05), ** (p = 0.0108), *** (p = 0.0297)