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. 2015 Mar 25;10(3):e0121643. doi: 10.1371/journal.pone.0121643

Table 3. Prevalence of specific IgG positive response against P. falciparum blood stage antigens in HEU and HUU children at different ages.

Age a Outcome AMA-1 MSP-119 MSP-3 PfSE GLURP R0 EBA-175 RII GLURP R2
HEU HUU P b HEU HUU P HEU HUU P HEU HUU P HEU HUU P HEU HUU P HEU HUU P
6 c % Pos f 16.1 51.9 0.04 * 6.5 14.8 0.40 0 3.7 0.47 6.5 3.7 1.0 3.2 7.4 0.59 22.6 22.2 1.0 6.45 11.1 0.66
12 d % Pos 3.5 0 1.0 12.0 44.0 0.025 * 20.7 11.1 0.47 3.45 14.8 0.19 13.8 14.8 1.0 41.8 33.3 0.59 10.3 14.8 0.70
18 e % Pos 6.9 7.7 1.0 13.8 26.9 0.31 17.2 11.5 0.71 13.8 11.5 1.0 48.3 23.1 0.09 6.9 19.2 0.24 10.3 7.7 1.0
Total % Pos 8.9 20.0 0.04 * 10.6 28.2 0.01 * 12.4 8.8 0.47 7.87 10.0 0.79 21.3 15.0 0.32 23.6 25.0 0.86 8.9 11.3 0.80

aAge in months

bP value determined by Fisher’s exact test for the comparison of the proportion of positive IgG responses

cNumber of samples at 6 months of age: HEU (n = 31) and HUU (n = 27)

dNumber of samples at 12 months of age: HEU (n = 29) and HUU (n = 27)

eNumber of samples at 18 months of age: HEU (n = 29) and HUU (n = 26)

fProportion (% Pos) of positive responders to each antigen

* Statistically significant difference at alpha level of 0.05