Table 3. EGFR formulas and endothelial activation in all, black, white, normal weight and obese patients with RA.
| All patients | Black patients | White patients | ||||
|---|---|---|---|---|---|---|
| MCP-1 | Angiopoietin 2 | MCP-1 | Angiopoietin 2 | MCP-1 | Angiopoietin 2 | |
| EGFR equation | β (SE); p | β (SE); p | β (SE); p | β (SE); p | β (SE); p | β (SE); p |
| Jelliffe | −0.002 (0.001); 0.04 | −0.001 (0.001); 0.2 | −0.001 (0.002); 0.6 | 0.001 (0.001); 0.4 | −0.003 (0.001); 0.02 | −0.001 (0.001); 0.2 |
| C-G ACBW | −0.002 (0.001); 0.05 | −0.001 (0.001); 0.05 | −0.000 (0.002); 0.8 | −0.000 (0.001); 0.8 | −0.003 (0.001); 0.01 | −0.002 (0.001); 0.04 |
| C-G IBW | −0.002 (0.001); 0.07 | −0.001 (0.001); 0.02 | 0.000 (0.002); 0.9 | −0.000 (0.001); 0.6 | −0.003 (0.001); 0.009 | −0.002 (0.001); 0.03 |
| C-G ADBW | −0.002 (0.001); 0.06 | −0.001 (0.001); 0.03 | −0.000 (0.002); 1.0 | −0.000 (0.001); 0.7 | −0.003 (0.001); 0.009 | −0.002 (0.001); 0.04 |
| C-G LBW | −0.003 (0.001); 0.04 | −0.002 (0.001); 0.006 | −0.000 (0.002); 0.9 | −0.001 (0.001); 0.3 | −0.004 (0.001); 0.008 | −0.003 (0.001); 0.01 |
| C-G NBW | −0.002 (0.001); 0.04 | −0.001 (0.001); 0.1 | −0.001 (0.002); 0.6 | −0.000 (0.001); 0.6 | −0.002 (0.001); 0.02 | −0.001 (0.001); 0.2 |
| Salazar-Corcoran | −0.002 (0.001); 0.06 | −0.001 (0.001); 0.04 | −0.000 (0.002); 1.0 | −0.000 (0.001); 0.8 | −0.003 (0.001); 0.009 | −0.002 (0.001); 0.04 |
| MDRD | −0.002 (0.001); 0.05 | −0.001 (0.001); 0.2 | −0.000 (0.002); 0.9 | 0.000 (0.001); 1.0 | −0.002 (0.001); 0.02 | −0.001 (0.001); 0.3 |
| CKD-EPI | −0.003 (0.001); 0.01 | −0.002 (0.001); 0.04 | −0.002 (0.002); 0.4 | −0.000 (0.001); 1.0 | −0.004 (0.002); 0.008 | −0.003 (0.001); 0.04 |
Data were analyzed in BMI, Framingham score, ethnicity, deformed joints, CDAI, chloroquine, leflunomide, penicillamine, prednisone and non-steroidal antiinflammatory agent use adjusted linear regression models.
Significant relations are shown in bold.
EGFR = estimated glomerular filtration rate, RA = rheumatoid arthritis, MCP-1 = monocyte chemoattractant protein-1, C-G = Cockcroft-Gault, AWB = actual body weight, IBW = ideal body weight, ADBW = adjusted body weight, LBW = lean body weight, NBW = no body weight, MDRD = Modification of Diet in Renal Disease, CKD-EPI = Chronic Kidney Disease Epidemiology Collaboration.