Table 5. Optimal cut-off EGFR values in ROC curves with corresponding characteristics and associations with plaque in black patients with RA.
| EGFR | Cut-off value | Sensitivity (%) | Specificity (%) | PPV (%) | NPV (%) | OR (95% CI) * | p * |
|---|---|---|---|---|---|---|---|
| Jelliffe | 64 | 45 | 82 | 24 | 72 | 3.61 (1.43–9.11) | 0.007 |
| C-G ACBW | 85 | 60 | 70 | 34 | 75 | 3.36 (1.46–7.75) | 0.004 |
| C-G IBW | 54 | 42 | 88 | 22 | 72 | 2.22 (0.95–5.21) | 0.07 |
| C-G ADBW | 68 | 55 | 81 | 29 | 75 | 2.72 (1.19–6.20) | 0.02 |
| C-G LBW | 49 | 58 | 79 | 30 | 76 | 3.31 (1.45–7.55) | 0.005 |
| C-G NBW | 73 | 45 | 84 | 24 | 72 | 4.00 (1.57–10.17) | 0.004 |
| Salazar-Corcoran | 79 | 55 | 81 | 29 | 75 | 2.72 (1.19–6.22) | 0.02 |
| MDRD | 64 | 35 | 91 | 18 | 70 | 2.49 (1.00–6.18) | 0.05 |
| CKD-EPI | 82 | 42 | 91 | 21 | 73 | 2.22 (0.95–5.22) | 0.07 |
Significant associations are shown in bold.
EGFR = estimated glomerular filtration rate, ROC = receiver operator characteristic, RA = rheumatoid arthritis, PPV = positive predictive value, NPV = negative predictive value, OR = odds ratio, CI = confidence interval, C-G = Cockcroft-Gault, AWB = actual body weight, IBW = ideal body weight, ADBW = adjusted body weight, LBW = lean body weight, NBW = no body weight, MDRD = Modification of Diet in Renal Disease, CKD-EPI = Chronic Kidney Disease Epidemiology Collaboration.
*Associations were assessed in modified Framingham score adjusted logistic regression models.