. Author manuscript; available in PMC: 2016 May 1.

Published in final edited form as: Bipolar Disord. 2014 Sep 25;17(3):248–256. doi: 10.1111/bdi.12260

Table 3. Multivariate regressions in BD subjects.

Model	Beta (standard error), p-value; standardized beta
Outcome:	Global Cognition
	F(2, 55)=26.6, p<0.0001, R²=0.49
Intercept	-12.5 (2.0), p<0.0001
Overall White Matter Integrity (Fractional Anisotropy)	24.5 (5.7), p<0.0001; stb=0.43
Education	0.180 (0.04), p<0.0001; stb=0.47
Outcome:	Overall White Matter Integrity (Fractional Anisotropy)
	F(2, 55)=16.4, p<0.0001 R²=0.37
Intercept	0.433 (0.02), p<0.0001
Lithium Duration (years)	0.0006 (0.0002), p=0.004; stb=0.33
Age	-0.001 (0.0002), p<0.0001; stb=-0.49
Outcome:	White Matter Hyperintensity Burden
	F(1, 56)=23.1, p<0.0001, R²=0.29
Intercept	-12.8 (1.2), p<0.0001
Age	0.088 (0.02), p<0.0001; stb=0.54

Log(X) transformation used for analyses