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. 2015 Feb 10;17(1):18. doi: 10.1186/s13058-015-0522-2

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© Lei et al.; licensee BioMed Central. 2015

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Quantile-quantile (QQ) plot of the observed P -values for associations with overall survival in estrogen receptor (ER)-negative patients who received chemotherapy. QQ plot shows the observed -log10 P-values (y axis) versus the expected -log10 P-values (x axis) for association of 3,610 SNPs in the immunosuppression pathway, with overall survival in ER-negative breast cancer patients who received adjuvant chemotherapy. The black dots indicate that there is inflation for observed associations.