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. 2015 Mar 3;3:6. doi: 10.1186/s40168-015-0069-6

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© Narrowe et al.; licensee BioMed Central. 2015

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Triclosan exposure shifts gut microbial community structure. (a) Samples cluster by exposure level immediately following acute triclosan exposure (day 7). After 1 week (b) and two weeks (c) of unexposed recovery (day 14 and day 21), samples are no longer separated by triclosan exposure history. Multi-response permutation procedure (MRPP) significance testing using the weighted UniFrac distance matrices shows that clustering of exposed and unexposed samples is highly non-random at day 7 (A = 0.194, P = 0.0003), but is no longer defined by exposure on day 14 (A = 0.056 P = 0.043) and day 21 (A = 0.003, P = 0.385).