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. Author manuscript; available in PMC: 2015 Mar 26.
Published in final edited form as: Mod Pathol. 2013 Nov 1;27(5):690–700. doi: 10.1038/modpathol.2013.188

Table 4.

Multivariate Cox proportional hazards model

Variable HR 95% CI P value
Histologic subtype
(vs. acinar predominant with <10% cribriform)
  Low grade 0.58 0.20–1.72 0.33
  Papillary 1.40 0.79–2.49 0.25
  Acinar predominant with ≥10% cribriform 1.88 1.02–3.45 0.042
  High grade 2.88 1.70–4.89 <0.001
Sex (male vs. female) 1.53 1.10–2.14 0.012
Surgery (sublobar vs. lobar) 3.23 2.24–4.66 <0.001
Stage (IB vs. IA) 1.97 1.38–2.80 <0.001
Lymphatic invasion 1.50 1.04–2.15 0.030
Necrosis 1.95 1.31–2.90 0.001
Mitotic count
  Intermediate vs. low 1.27 0.77–2.07 0.35
  High vs. low 1.46 0.93–2.31 0.10

Significant p-values are shown in bold.

HR, Hazard ratio; CI, confidence interval