. Author manuscript; available in PMC: 2015 Mar 26.

Published in final edited form as: J Nucl Cardiol. 2014 Mar 29;21(3):453–466. doi: 10.1007/s12350-014-9865-9

Table 3.

Multivariable model estimating all-cause mortality in 2,820 symptomatic patients with a luminal stenosis

	Hazard ratio	95% CI for HR		Wald χ²	P value
	Hazard ratio	Lower	Upper	Wald χ²	P value
Univariable models estimating all-cause mortality
CAC (per category)^*	1.85	1.35	2.53	15	<.0001
CAC				39	<.0001
100–399	2.88	1.45	5.72	9	.002
≥400	6.76	3.45	13.27	31	<.0001
Multivariable model estimating all-cause mortality
CAC (per category)^*	1.99	1.41	2.82	15	<.0001
CAC				15	.001
100–399	2.10	1.05	4.21	4	.036
≥400	3.87	1.91	7.82	14	<.0001
Multivariable model estimating death or MI
CAC (per category)^*	1.81	1.30	2.50	13	<.0001
CAC				12	.002
100–399	2.05	1.09	3.83	5	.025
≥400	3.22	1.65	6.28	12	<.0001

For these models, CAC scores < 100 were collapsed into one category as they had similar event rates. Multivariable mortality model χ² = 92, P < .0001, multivariable death or MI model χ² = 84, P < .0001; clinical covariates: age and other cardiac risk factors (overall mortality at 4 years: 2.8%, 50 deaths, death or MI at 4 years: 3.3%, 58 events).

Per category: 0 (comparator) vs <100, 100–399, and ≥400.