Table 1.
Model antibody fragments used in this study.
| Antibody | Target | VH |
VL |
|||
|---|---|---|---|---|---|---|
| V | D | J | V | J | ||
| SH527-IIA4 | SMAD2-P | IGHV3–30*03 | IGHD3–22*01 | IGHJ4*02 | IGLV2–14*02 | IGLJ3*02 |
| SH527-IIC10 | SMAD2, SMAD2-P | IGHV5–51*01 | IGHD2–15*01 | IGHJ3*02 | IGLV1–50*01 | IGLJ3*02 |
| SH855-C11 | CXCR5 | IGHV1–69*01 | IGHD3–10*01 | IGHJ4*02 | IGLV1–47*02 | IGLJ3*01 |
The most similar human germline genes were identified by VBASE 2 (http://www.vbase2.org).
VH = variable domain of the heavy antibody chain; VL = variable domain of the light antibody chain; V = variable gene segment; D = diversity gene segment; J = Joining gene segment