Figure 1.

Noncoding variants shared among individuals by mode of inheritance. Shown are number of single nucleotide variants present at each allele frequency assuming either an autosomal recessive (top) or autosomal dominant (bottom) model of inheritance in each of the ten individuals sequenced. Grey bars indicate the number of variants identified using basic frequency cutoffs described in text and Supplementary Methods. Black bars indicate the number of variants remaining after filtering out those present in any of the three control genomes.