FIG. 8.

Step response and adaptation of ipRGCs. A: an ipRGC recorded in the flat-mount rat retina under current clamp, showing sustained firing during long steps of light. Numbers to the left of each trace represent the log irradiance (500 nm photons·cm⁻²·s⁻¹). [Modified from Berson et al. (17).] B: adaptation to light in spike-firing by ipRGCs in current clamp. C: adaptation of intrinsic photocurrent, recorded in voltage clamp, to light. [B and C modified from Wong et al. (227).] All recordings with synaptic transmission blocked and at room temperature.