Table 3. Effects of the biochanin A on gastric ulcer area, inhibition percentage and alcian blue binding capacity.
Animal’s group | pH | GWM (mg Alcian blue/g tissue) | Ulcer Area (mm)2 | Inhibition (%) |
---|---|---|---|---|
Group1 (10%Tween 20) (ulcer control) | 3.51 + ±0.04 | 130.05 ± 5.11 | 755.08 ± 20.17 | - |
Group 2 Omeprazole (20 mg/kg) | 6.13 ±0.05* | 621.18 ± 6.15* | 172.45* ±19.22* | 77.16%* |
Group 3 Biochanin A (25 mg/kg) | 4.88 ±0.04* | 410.45 ± 5.22* | 285.39 ± 6.86* | 62.2%* |
Group 4 Biochanin A (50 mg/kg) | 5.78±0.06* | 548.33 ± 4.16* | 191.15 ±10.78* | 74.68%* |
Alcian blue binding capacity is defined as Gastric wall mucus (GWM).
Values expressed as mean ± S.E.M. There are no statistically significant differences between the measurements in different groups. The significant value was set at P < 0.05, compared with cancer control group.