Table 2. Characteristics of 14 anti-MCPyV mAbs produced with VP1 from MCC350 and MKT21 strains.
BL, buried linear, C, conformational.
| Name | Ig isotype | Type of epitope | PyV Type specificity | Neutralization |
|---|---|---|---|---|
| MCC350-A1B | IgG2a | BL | ND | - |
| MCC350-D5D | IgG3 | BL | ND | - |
| MCC350-B4A | IgG3 | BL | ND | - |
| MCC350-D1D | IgG3 | BL | ND | - |
| MCC350-C1A | IgG2a | BL | ND | - |
| MCC350-B1C | IgG3 | BL | ND | - |
| MCC350-B6B | IgG3 | BL | ND | - |
| MKT21-1D1 | IgG3 | C | MCPyV | + |
| MKT21-1D3 | IgG3 | C | MCPyV | + |
| MKT21-1D4 | IgG2a | C | MCPyV | + |
| MKT21-3D2 | IgM | C | MCPyV | + |
| MKT21-3D3 | IgM | C | MCPyV | + |
| MKT21-5D2 | IgG2a | C | MCPyV | + |
| MKT21-6A6 | IgG3 | C | MCPyV | + |
| Anti-BKPyV | ND | C | BKPyV | ND |
| Anti-SV40 | ND | C | SV40 | ND |
| MKT21 polyclonal | ND | ND | MCPyV, SV40, LPyV, BKPyV | + |