Table 3. Serum biomarkers of patients with EGPA based on prednisone usage at time of study visit.
Serum parameters | No pred. use (n = 24) | Pred. use (n = 81) | MWU | LR |
---|---|---|---|---|
Eotaxin-3 [pg/ml] | 9.7 (0–549.8) | 0 (0–555.5) | 0.004 | 0.021 |
TARC/CCL17 [pg/ml] | 393.6 (129.3–1918.0) | 285.5 (77.1–4549.4) | 0.18 | 0.67 |
IgG4 [mg/dL] | 21.5 (7.0–281.0) | 47.0 (7.0–479.0) | 0.038 | 0.099 |
IgG4/IgG ratio*100 | 3.4 (0.1–22.0) | 6.0 (1.0–32.0) | 0.52 | 0.19 |
ESR [mm/1st hour] | 5.0 (1–40.0) | 5.0 (1–40) | 0.80 | 0.084 |
CRP [mg/L] | 2.9 (0.1–32.9) | 2.2 (0.1–21.0) | 0.41 | 0.20 |
Eosinophils (%) | 8.0 (1–50.0) | 4.0 (0.1–43.0) | <0.001 | 0.006 |
Data are shown as median (range in parenthesis); EGPA: eosinophilic granulomatosis with polyangiitis (Churg-Strauss); LR, Logistic regression analysis as described in Materials and Methods; MWU, Mann Whitney U test; n, number of visits; pred., prednisone