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. 2015 Mar 26;10(3):e0121737. doi: 10.1371/journal.pone.0121737

Table 3. Serum biomarkers of patients with EGPA based on prednisone usage at time of study visit.

Serum parameters No pred. use (n = 24) Pred. use (n = 81) MWU LR
Eotaxin-3 [pg/ml] 9.7 (0–549.8) 0 (0–555.5) 0.004 0.021
TARC/CCL17 [pg/ml] 393.6 (129.3–1918.0) 285.5 (77.1–4549.4) 0.18 0.67
IgG4 [mg/dL] 21.5 (7.0–281.0) 47.0 (7.0–479.0) 0.038 0.099
IgG4/IgG ratio*100 3.4 (0.1–22.0) 6.0 (1.0–32.0) 0.52 0.19
ESR [mm/1st hour] 5.0 (1–40.0) 5.0 (1–40) 0.80 0.084
CRP [mg/L] 2.9 (0.1–32.9) 2.2 (0.1–21.0) 0.41 0.20
Eosinophils (%) 8.0 (1–50.0) 4.0 (0.1–43.0) <0.001 0.006

Data are shown as median (range in parenthesis); EGPA: eosinophilic granulomatosis with polyangiitis (Churg-Strauss); LR, Logistic regression analysis as described in Materials and Methods; MWU, Mann Whitney U test; n, number of visits; pred., prednisone