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. 2015 Mar 26;10(3):e0121134. doi: 10.1371/journal.pone.0121134

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© 2015 Valiente-Soriano et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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Fig 7 — A: Serial coronal brain sections spanning the right (contralateral) superior colliculus (from anterior/posterior bregma coordinates: -3.08 to -4.72 mm) showing the retinal afferents labelled by anterograde tracing with CTB injected into the left eye. Left column: control SC. The remaining three columns show a representative example of a SC analyzed at 10 days, 8 weeks or 14 weeks after ocular hypertension (OHT). B: Plots of the area occupied by retinal afferents in the SC against the anterior-posterior distance (Bregma coordinates, in mm). These plots correspond to the SCs shown in A. C: Volume of the SC occupied by retinal afferents. n = number of SC analyzed. Compared to control SC, the volume of SC innervated by retinal axons decreases significantly after OHT (t-test p<0.001).