Fig. 4.
Regression analysis of pLTF magnitude vs. the change in mean arterial pressure during hypoxia (A), or the change in mean arterial pressure during an experimental protocol (B; 60 min post-AIH vs. baseline). In (A), there was no significant correlation between the change in MAP during hypoxia and pLTF (P = 0.24, r2 = 0.124) in vehicle-treated (●, n = 7) and/or PPADS-treated (○, n = 8) rats. Similarly (B) MAP at 60 min post-AIH and pLTF are not significantly correlated (P = 0.72, r2 = 0.01) in PPADS-treated rats. However, a significant correlation was apparent between pLTF and MAP at 60min post-AIH in vehicle-treated rats (P = 0.01, r2 = 0.717). This latter observation is not consistent with numerous previous observations from our laboratory and is regarded as a spurious result here (see discussion; Baker-Herman and Mitchell, 2008).