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. Author manuscript; available in PMC: 2016 Apr 1.
Published in final edited form as: Exp Hematol. 2014 Dec 27;43(4):319–330.e10. doi: 10.1016/j.exphem.2014.12.005

Figure 3. Colony forming ability of B-cell progenitors is significantly reduced in Hspa9+/− compared to Hspa9+/+ mice.

Figure 3

A) The number of Hspa9+/− CFU-PreB colonies counted on day 7 were significantly reduced compared to colonies from Hspa9+/+ littermate bone marrow at all ages evaluated. B) Representative images of CFU-PreB colonies. Percentage of bone marrow cells that are common lymphoid progenitors (C) and Hardy fractions (D) were not significantly different between Hspa9+/− and Hspa9+/+ littermate mice at 4–5 months of age. (Hspa9+/+, filled circles; Hspa9+/−, open circles) CLP, common lymphoid progenitor. Statistical analysis by two tailed Student’s t-test. *p<0.05, **p<0.01, ***p<0.001