Table 1.
Physiologic parameters in mice fed diets containing different levels of iron
| Variables | LN | HN | H |
|---|---|---|---|
| Hemoglobin (g/dL) | 16.4 ± 0.5 | 15.6 ± 1.4 | 16.7 ± 1.7 |
| Hematocrit (%) | 47.9 ± 1.6 | 45.3 ± 3.4 | 47.6 ± 4.0 |
| Insulin (ng/mL) | 1.73 ± 0.65 | 1.52 ± 0.45 | 2.15 ± 0.38 |
| Glucagon (pg/mL) | 67.1 ± 5.5 | 60.4 ± 5.5 | 78.1 ± 8.7 |
| Body weight‡ (g) | 29.89 ± 0.27** | 28.09 ± 0.25 | 28.65 ± 0.176 |
| Total liver iron§ (μg/g wet weight) | 158.1 ± 21.4* | 239.4 ± 42.5 | 583.3 ± 79.3** |
| Transferin saturation (%) | 44.1 ± 4.1 | 45.6 ± 4.9 | 58.5 ± 3.1* |
| Available 59Fe absorption (%) | 41.3 ± 4.2** | 22.4 ± 3.1 | 8.8 ± 1.5* |
*P ≤ 0.05, **P ≤ 0.01, by two-tailed ANOVA with Tukey post hoc analysis compared with HN.
‡N = 72/group.
§Measured by inductively coupled plasma MS.