Figure 3.
Hepatic Sesn3 deficiency affects the Akt signaling pathway. A: Signaling analysis of livers from WT and Sesn3-LKO mice after overnight starvation. B: Signaling analysis of WT and Sesn3-LKO livers after the animals were starved overnight and then fed for 4 h. C: Quantitative data from panel A. D: Quantitative data from panel B. Data were normalized by calculating the ratio of each signaling event in the Sesn3-LKO and comparing it to that in the WT mice. Data are presented as mean ± SEM. *P < 0.05, WT vs. Sesn3-LKO mice.