Skip to main content
. Author manuscript; available in PMC: 2016 May 1.
Published in final edited form as: Gen Comp Endocrinol. 2014 Sep 26;215:106–116. doi: 10.1016/j.ygcen.2014.09.010

Figure 6. Variation of RAS proteins in the multiple rat genomes.

Figure 6

A) Nonsynonymous mutations identified in the multiple rat genomes (left) for several of the RAS genes (top). B) Based on structural assessment of all rat variants, the amino acid 154 (red) variant of AGT (gray) is in close proximity to contacts with Renin (cyan). C) Amino acid 90 (red) variant of ACE2 (gray) is a cite of known site for N-linked glycosylation (blue) while amino acid 509 variant is located close to Ang II (cyan) binding. D) Amino acid 40 (red) variant in AT1b (gray) is located at a membrane (cyan) contact point on a helix with known contacts with the Ang II peptide (blue).