Table 2. AutoDock of Ang peptides to various receptors.

Binding energies (kcal/mol) from AutoDock experiments for N- and C-terminal domains of ACE, ACE2, Neprilysin, and PRCP to the various Ang peptides with the top five binding energies shown for each docking run. The top binding energy for each is shown in the top line.

	Ang I	Ang-(1-9)	Ang II	Ang III	Ang IV	Ang-(1-7)	Ang-(1-5)
ACE C-term	10.11	10.18	10.26	10.61	10.1	8.29	8.32
	9.1	9.54	9.91	10.35	9.43	6.99	7.29
	8.07	8.72	9.55	9.98	8.53	6.98	7.25
	7.88	8.56	9.32	9.86	8.33	6.68	7.11
	7.36	8.51	9.24	9.86	8.31	6.51	6.52
ACE N-term	9.73	7.5	9.63	9.77	9.14	8.56	6.58
	8.54	7.23	8.61	8.07	8.74	6.79	6.45
	7.87	7.16	8.43	7.46	8.69	6.14	6.42
	7.65	7.12	8.15	6.89	8.47	6.13	6.16
	7.53	6.97	8.05	6.87	8.45	6.09	5.96
ACE2	3.4	4.58	5.94	6.51	7.22	2.4	5.82
	2.69	4.41	4.97	4.67	6.75	1.98	5.58
	2.25	3.42	3.51	4.62	6.61	0.95	5.41
	1.6	3.26	3.37	4	6.05	0.57	4.93
	1.55	3.26	3.21	3.93	5.85	0.49	4.79
Neprilysin	4.43	8.03	9.5	8.4	8.23	10.32	7.61
	3.69	6.89	6.92	7.02	7.71	6.61	7.44
	3.57	5.18	5.34	6.6	7.4	6.38	5.87
	3.2	4.66	5.04	6.31	7.27	6.27	5.67
	3.14	4.5	4.54	6.12	7.09	5.95	5.34
PRCP	5.73	6.54	5.74	7.21	6.4	1.9	4.82
	5.4	6.51	5.49	6.69	6.18	0.82	4.32
	4.69	5.83	5.28	6.32	6.15	0.76	4.3
	4.65	5.52	4.9	6	6.09	0.7	4.25
	4.54	5	4.59	5.76	5.98	0.54	4.15